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Latest Suntheanine® research findings:
A combination of green tea extract and L-Theanine improves memory and attention in subjects with mild cognitive impairment: A double-blind placebo-controlled study.
Sang-Ki Park, JOURNAL OF MEDICINAL FOOD J Med Food 14 (4) 2011, 334–343
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Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: A randomized controlled trial.
Matsumoto et al. BMC Complementary and Alternative Medicine 2011, 11:15
http://www.biomedcentral.com
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L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
Ritsner, M.S., et al. J Clin Psychiatry, November 2010.
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Cystine and theanine supplementation restores high-intensity resistance exercise-induced attenuation of natural killer cell activity in well-trained men.
Kawada, S. J strength and conditioning research. 24(3): 846-851, 2010.
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Effects of L-Theanine in attention and reduction time response.
Higashiyama. Journal of functional foods. 200mg L-theanine. 18 normal healthy volunteer University students. (publication pending) 2010.
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L-theanine to reduces stress and anxiety syndrome in middle aged american women.
Kapoor, M.P. Publication pending (data presented at FASEB). 200mg L-theanine, 135 subjects. 2010.
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Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial.
Murakami, S. Biosci Biotechnol Biochem. April 23.; 73(4):817-21. 2009.
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Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells.
Liu. Q. Cytotecnology. 59:211-217. 2009.
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L-theanine, y-glutamylethylamide, a unique amino acid leaves, modulates neurotransmitter concentrations in striatum interstitium in conscious rats.
Yamada, T. Amino Acids. 36:21-27. 2009
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L-theanine. an amino acid in green tea, attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity: reduction in oxidative damage and inactivation of ERK/p38 kinase and NF-kappaB pathways.
Kim, T. Re Radic Biol Med. 1;47(11): 1601-10. Dec. 2009.
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Standardized capsule of Camelia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo controlled study.
Nantz, M.P. Nutrtion February 2009.
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A study of L-theanine and daytime drowsiness.
Ozeki, M. JSPA, Vol 13, No 1, 2008, pp 9-15.
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Altered levels of oxidation and phospholipase C isozyme expression in the brains of theanine-administered rats.
Nishida, K. Biol. Pharm. Bull 31 (5) 857-860 (2008)
www.ncbi.nlm.nih.gov
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Effects of L-theanine, a unique amino acid in tea leaves, on memory.
Yamada, T. Biosci Biotechnol Biochem, Vol. 72, No. 5, May 2008.
www.ncbi.nlm.nih.gov
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Efficacy (against premenstrual syndrome) and short term safety of L-theanine in a randomized, double-blind, parallel-group study in humans.
Timmcke, J. The FASEB journal. 2008.
www.fasebj.org
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L-theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance.
kelley, S. Journal of Nutrition, Vol 138, No.8, August 2008.
www.ncbi.nlm.nih.gov
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L-Theanine elicits an umami taste with inosine 5'-monophosphate
Narukawa, M. Biosci. biotechnol. Biochem, 72 (11), 3015-3017,2008
www.ncbi.nlm.nih.gov
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L-theanine intervention enhances human lymphocyte function
Bukowski, J. Nutritional Reviews Vol. 66(2); 96-102, 2008
www.ncbi.nlm.nih.gov
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L-theanine, a natural constituent in tea, and its effect on mental state in humans.
Nobre, A. Asia Pac J Clin Nutr., Vol. 17, 2008.
www.ncbi.nlm.nih.gov
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Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death.
Cho, H.S. NeuroToxicology 656-662 (2008)
www.ncbi.nlm.nih.gov
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Psychological effects of dietary components of tea; caffeine and L-theanine.
Bryan, J. Nutr. Rev., Vol 66, 2, pp 82-90. Feb 2008.
www.ncbi.nlm.nih.gov
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Standardized capsule of camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study.
Nantz P., Meri. et al./Nutrition (2008)
www.ncbi.nlm.nih.gov
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The combined effects of L-theanine and caffeine on cognitive performance and mood.
Owen, G. Nutr.Neurosci. Vol. 11, No.4, August 2008.
www.ncbi.nlm.nih.gov
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The effects of L-theanine on automatic nervous system during sleep in postmenopausal woman.
Ozeki, M. JSPA, Vol 13, No 3, 2008, pp 147-154.
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The effects of L-theanine, caffeine and their combination on cognition and mood.
Haskell, C.F Biol Psychol, Vol 77, 2, pp 113-22, Feb 2008.
www.ncbi.nlm.nih.gov
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Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.
Egashira, N. Phytotherapy research, Phytother. Res 22, 65-68 (2008)
www.ncbi.nlm.nih.gov
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Theanine, an ingredient of green tea, inhibits Glutamine transport in neurons and astroglia in rat brain.
Kakuda, T. Journal of Neuroscience Research 86:1846-1856 (2008)
www.ncbi.nlm.nih.gov
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Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
Rogers, PJ. Psychopharmacology, Vol 195, 4, pp 569-577, Jan 2008.
www.ncbi.nlm.nih.gov
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The deployment of intersensory selective attention: a high-density electrical mapping study of the effects of theanine.
Ramirez M, et al., Clin Neuropharmacol, Jan-Feb 2007
www.ncbi.nlm.nih.gov
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Suntheanine reduces psychological and physiological stress responses.
Kimura K, et al., Biol Psychol, Aug 21 2006.
www.ncbi.nlm.nih.gov
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Pharmacology and therapeutic uses of L-theanine.
Eschenauer G, et al. American J. Health-Syst Pharm, Vol 63, Jan 1, 2006.
www.ncbi.nlm.nih.gov
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Factors that Affect the Body’s Nervous System: Relaxation Effects of Suntheanine.
Ozeki M et. al., Nutraceutical Proteins and Peptides in Health and Disease, CRC Press, 2006, pp 377-390.
www.crcpress.com
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Effects of Suntheanine on alcohol metabolism and hepatic toxicity.
Sadzuka Y., Biol Phar. Bull., Vol 28, No 9, September 2005.
www.ncbi.nlm.nih.gov
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Effects of Suntheanine on neurotransmitter release and its relationship with glutamic acid neurotransmission.
Yamada T., Nutritional Neuroscience, August 2005, 219-226.
www.ncbi.nlm.nih.gov
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L-theanine intervention enhances human gamma delta T lymphocyte function.
Bukowski, J. Nutr Rev, Vol 66, 2, pp 96-102. Feb 2008.
www.ncbi.nlm.nih.gov
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L-theanine, r-glutamylethlamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation.
Yamada, T. Life Sciences. Vol 81, 16, pp 1247-1255. 2007.
www.ncbi.nlm.nih.gov
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Pharmacokinetics of Suntheanine shown. Poor absorption, unkown safety and efficacy of racemic mixtures confirmed.
Desai MJ, Gill MS, Hsu WH, Armstrong DW. Chirality 17:154-162, March 2005.
www.ncbi.nlm.nih.gov
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Suntheanine shown to enhance the therapeutic efficacy of doxorubicin.
Sugiyama T, Sadzuka Y, Tanaka K, Sonobe T. Tox Lett 2001 Apr 30;121(2):89-96.
www.ncbi.nlm.nih.gov
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Effect of Suntheanine on brain monoamines, striatal dopamine release and behavior.
Yokogoshi H, Terashima T. Nutrition 2000, Sep; 16(9):776-777.
www.ncbi.nlm.nih.gov
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Effect of Suntheanine Intake on Learning Ability.
Terashima T. et al. Fourth Shizuoka Forum on Health and Longevity. Nov 18, 1999 p.82-83.
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Suntheanine and its relaxation effect in humans.
Juneja LR, Trends in Food Sci. Tech. June 1999. v10 (6/7) p. 199-204.
www.sciencedirect.com
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Suntheanine induced reduction of brain serotonin.
Yokogoshi H, et al. Biosci Biotechnol Biochem. 1998 Apr;62(4):816-7.
www.ncbi.nlm.nih.gov
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Effects of Suntheanine on the release of alpha waves in human volunteers.
Kobayashi A, et al. Nippon Nogeikagaku Kaishi. 1998 v72, 153-157.
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Effect of Suntheanine on brain monoamines and dopamine.
Yokogoshi H, et al. Neurochem Res. 1998 May;23(5):667-73.
www.ncbi.nlm.nih.gov
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Hypotensive effect of Suntheanine
Yokogoshi H, et al. Life Sci. 1998;62(12):1065-8.
www.ncbi.nlm.nih.gov
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Effect of Suntheanine on norepinephrine and serotonin levels.
Kimura R, et al. Chem Pharm Bull (Tokyo). 1986 Jul;34(7):3053-7.
www.ncbi.nlm.nih.gov
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Suntheanine shown to reduce adverse reactions of doxorubicin.
Sugiyama T. Cancer Letters, 2004 Aug 30, Vol 212, pp 177-84.
www.ncbi.nlm.nih.gov
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Possible neuroprotective effect of Suntheanine.
Nagasawa, K. Biochem. And Biophys. Research Communications 320 (2004) 116-122.
www.ncbi.nlm.nih.gov
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Neuroprotective effect of Suntheanine on cerebral infarction.
Egashira, N. Neuroscience Letters, 2004, Vol 363, pp 58-61.
www.ncbi.nlm.nih.gov
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Anti-obesity effects of Sunphenon and Suntheanine.
Zheng G, Sayama K, Okubo T, Juneja LR, Oguni I. In Vivo, Vol 18, 2004 Jan. pp 55-62.
www.ncbi.nlm.nih.gov
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Effects of Suntheanine on brain alpha waves in adult males.
Song, Chan Hee. Dept. of Family Medicine, Obesity Clinic, St. Mary’s Hospital, Catholic University of Korea. The Korean Nutrition Society. 2003 36(9): 918-923.
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Analysis of theanine enantiomers by HPLC/atmospheric pressure ionization-mass spectrometry. Suntheanine only true L-theanine.
Desai MJ, Armstrong D.W. Rapid Commun Mass Spectrom, Vol 18, 2004, pp. 251-6.
www.ncbi.nlm.nih.gov
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Effect of Suntheanine on doxorubicin-induced adverse reaction.
Sugiyama T. Proceedings of the AACR, Vol 44, 2nd ed., July 2003.
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Suntheanine enhances efficacy of chemotherapeutic agents.
Sugiyama T, Sadzuka Y. Biochim Biophys Acta. 2003 Dec 5.
www.ncbi.nlm.nih.gov
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Glutamate transporter mediated increase of antitumor activity of Suntheanine
Sadzuka Y, et. al., Yakugaku Zasshi No. 11 2002 Nov pp. 995-9, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan.
www.ncbi.nlm.nih.gov
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Improving Effect of Suntheanine on Premenstrual Syndrome
Ueda T. et al. Journal of JSPOG Vol. 6, No. 2, pp 234-239, Dec 2001.
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Effect of brain alpha wave activity and golf performance by Suntheanine.
Kim K, Yum K, Lee Y. Int'l Symposium on Food, Nutrition and Health, Korean Society of Food Science and Nutr. Dec 7-8, 2001: 50-51.
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Correlations between central nervous parameters and hormonal regulations during recovery from physical stress influenced by Suntheanine.
Weiss M, Schnittker R, Barthel T, Falke W, Juneja L.R. Amino Acids (Vienna) 2001 Aug; Vol. 21, No. 1, PP 62.
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Effects of L-theanine, a unique amino acid in tea leaves, on memory.
Yamada, T. Biosci Biotechnol Biochem, Vol. 72, No. 5, May 2008.www.ncbi.nlm.nih.gov
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Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multi-drug resistance.
Sadzuka Y, et al. Toxicol Lett. 2000 Apr 3;114(1-3):155-62.
www.ncbi.nlm.nih.gov
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